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Anti -ICAM1 Rabbit pAb

价格: 在线咨询
货号:
DRF101180
产品规格:
100 μL
Applications:
WB/IHC/IF
Species:
H/M,M/R,M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

ICAM 1 rabbit polyclonal

Protein full name

Intercellular adhesion molecule 1

Synonyms

ICAM1, BB2, CD54, P3.58, intercellular adhesion molecule 1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse ICAM-1

Isotype

IgG

Predicted MW.

58 kDa

Observed MW.

58 kDa

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

P05362Q00238P13597



Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 1000-1: 3000

kidney, liver,lung

IHC

Mouse, Rat

1: 800-1: 6000

liver, kidney

IF

Mouse, Rat

1: 500-1: 1000

lung



Background


ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

(Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins . Acts as a receptor for Coxsackievirus A21 capsid proteins . Upon Kaposis sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell .




Images




Western blot analysis of ICAM 1 (GB11106) at dilution of 1: 1000

Lane 1: Mouse liver tissue lysate

Lane 2: Mouse lung +LPS tissue lysate

Lane 3: Mouse kidney tissue lysate

Immunohistochemistry analysis of paraffin-embedded mouse kidney ICAM 1 (GB11106) at dilution of 1: 1500

Immunohistochemistry analysis of paraffin-embedded rat kidney ICAM 1 (GB11106) at dilution of 1: 1500


Immunohistochemistry analysis of paraffin-embedded mouse liver ICAM 1 (GB11106) at dilution of 1: 1500



Immunofluorescence analysis of paraffin-embedded mouse lung using ICAM 1 (GB11106) at dilution of 1: 500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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