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Anti -Junctional Adhesion Molecule 1/JAM-A Rabbit pAb

价格: 在线咨询
货号:
DRF101183
产品规格:
100 μL
Applications:
WB
Species:
H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

JAM-A rabbit polyclonal

Protein full name

Junctional adhesion molecule A

Synonyms

JAM-A, Junctional adhesion molecule 1, JAM-1, CD321, F11r, Jam1, Jcam, Jcam1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse JAM-A

Isotype

IgG

Purity

Affinity purification

Predicted MW.

33 kDa

Observed MW.

35 kDa

Uniprot ID

Q9Y624, O88792, Q9JHY1




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, colon, small intestine




Background


Seems to play a role in epithelial tight junction formation. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin super family gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.




Images


Western blot analysis of JAM-A

(GB111062) at dilution of 1: 1000

Lane 1: Caco2 cell lysate

Lane 2: SW480 cell lysate

Lane 3: Mouse liver tissue lysate

Lane 4: Mouse colon tissue lysate

Lane 5: Rat liver tissue lysate

Lane 6: Rat small intestine tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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