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Anti -KAT5 / Tip60 Rabbit pAb
价格：
在线咨询
货号：
DRF101186
产品规格：
100 μL
Applications：
IHC/IF
Species：
H/M/R,H/M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
Tip60 rabbit polyclonal |
|
Protein full name |
Histone acetyltransferase KAT5 |
|
Synonyms |
60 kDa Tat-interactive protein, Tip60, Histone acetyltransferase HTATIP, Kat5, Lysine acetyltransferase 5, Htatip, Tip60 |
|
Immunogen |
Recombinant protein corresponding to Mouse Tip60 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
lung cancer, breast cancer, brain, heart |
|
IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
lung cancer, breast cancer, brain, heart |
Background
Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human lung cancer using Tip60 (GB111065) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded human breast cancer tumor using Tip60 (GB111065) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded mouse brain using Tip60 (GB111065) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat brain using Tip60 (GB111065) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat heart using Tip60 (GB111065) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室