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Anti -SRC3 Rabbit pAb
价格：
在线咨询
货号：
DRF101187
产品规格：
100 μL
Applications：
IHC
Species：
H/M/R,H/M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
SRC3 rabbit polyclonal |
|
Protein full name |
Nuclear receptor coactivator 3 |
|
Synonyms |
NCoA-3, AIB-1, CBP-interacting protein, pCIP, RAC-3, SRC-3, ACTR, TRAM-1, Ncoa3, Aib1, Rac3, Tram1 |
|
Immunogen |
Recombinant protein corresponding to Mouse SRC3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
breast cancer, ovary, brain |
|
IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
breast cancer, ovary, brain |
Background
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. SRC3 is an oncogene that is reported to be amplified and overexpressed in breast and gastric cancer and stimulates AKT signaling and cell growth and tumorigenesis.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human breast cancer using SRC3 (GB111066) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse ovary using SRC3 (GB111066) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using SRC3 (GB111066) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat brain using SRC3 (GB111066) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室