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Anti -SHP2 Rabbit pAb

价格: 在线咨询
货号:
DRF101197
产品规格:
100 μL
Applications:
WB
Species:
H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

SHP2 rabbit polyclonal

Protein full name

Tyrosine-protein phosphatase non-receptor type 11

Synonyms

Protein-tyrosine phosphatase SYP, SH-PTP2, SHP2, Ptpn11

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse SHP2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

68 kDa

Observed MW.

72 kDa

Uniprot ID

Q06124, P35235, P41499




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

ovary




Background


The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.




Images


Western blot analysis of SHP2 (GB111075) at dilution of 1:1000

Lane 1: K562 cell lysate
Lane 2: SKBR3 cell lysate
Lane 3: Mouse ovary tissue lysate
Lane 4: Rat ovary tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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