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Anti -eIF-6 Rabbit pAb

价格: 在线咨询
货号:
DRF101225
产品规格:
100 μL
Applications:
WB
Species:
H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

eIF-6 rabbit polyclonal

Protein full name

Eukaryotic translation initiation factor 6

Synonyms

eIF-6, B4 integrin interactor, CAB, p27(BBP), Eif6, Itgb4bp

Immunogen

Recombinant protein corresponding to

Mouse eIF-6

Isotype

IgG

Purity

Affinity purification

Predicted MW.

27 kDa

Observed MW.

29 kDa

Uniprot ID

P56537, O55135, Q3KRD8




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

testes, adipose




Background


Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene.




Images


Western blot analysis of eIF-6 (GB111101) at dilution of 1:1000

Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: HEK293 cell lysate
Lane 4: Mouse testes tissue lysate
Lane 5: Mouse adipose tissue lysate
Lane 6: Rat testes tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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