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Anti -UBE2D3 Rabbit pAb

价格: 在线咨询
货号:
DRF101227
产品规格:
100 μL
Applications:
Species:
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

UBE2D3 rabbit polyclonal

Protein full name

Ubiquitin-conjugating enzyme E2 D3

Synonyms

(E3-independent) E2 ubiquitin-conjugating enzyme D3, E2 ubiquitin-conjugating enzyme D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2(17)KB 3, Ubiquitin-protein ligase D3, Ube2d3

Immunogen

Recombinant protein corresponding to Mouse UBE2D3

Isotype

IgG

Purity

Affinity purification

Predicted MW.

17 kDa

Observed MW.

17 kDa

Uniprot ID

P61077, P61079, P61078




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, liver, testis




Background


The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes, ubiquitin-activating enzymes or E1s, ubiquitin-conjugating enzymes or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.




Images


Western blot analysis of UBE2D3 (GB111103) at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: NIH/3T3 cell lysate
Lane 3: MCF7 cell lysate
Lane 4: Mouse brain tissue lysate
Lane 5: Mouse liver tissue lysate
Lane 6: Mouse testis tissue lysate
Lane 7: Rat brain tissue lysate
Lane 8: Rat liver tissue lysate
Lane 9: Rat testis tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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