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产品详情
操作说明
注意事项
Product Information
|
Description |
SYT1 rabbit polyclonal |
|
Protein full name |
Synaptotagmin-1 |
|
Synonyms |
Synaptotagmin I, SytI, p65, DKFZp781D2042, FLJ42519, SVP65, Syt2 |
|
Immunogen |
Recombinant protein corresponding to Mouse SYT1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell Membrane |
|
Predicted MW. |
47 kDa |
|
Observed MW. |
60 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cortex, hippocampus |
|
IHC |
Human |
1: 1000-1: 4000 |
lung cancer |
Background
This protein calcium sensor that participates in triggering neurotransmitter release at the synapse . May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
Images
|
|
Western blot analysis of SYT1 (GB111130) at dilution of 1: 1000 Lane 1: Mouse brain tissue lysate Lane 2: Mouse cortex tissue lysate Lane 3: Mouse hippocampus tissue lysate Lane 4: Rat brain tissue lysate Lane 5: Rat cortex tissue lysate Lane 6: Rat hippocampus tissue lysate |
|
|
Immunohistochemistry analysis of paraffin-embedded human lung cancer using SYT1 (GB111130) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
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