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Anti -BRCA2 Rabbit pAb
价格：
在线咨询
货号：
DRF101262
产品规格：
100 μL
Applications：
IHC/IF
Species：
M/R,M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
BRCA2 rabbit polyclonal |
|
Protein full name |
Breast cancer type 2 susceptibility protein |
|
Synonyms |
Brca2, BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11, Breast cancer 2, DNA repair associated, breast cancer 2, Early onset, BRCA2 DNA repair associated |
|
Immunogen |
Recombinant protein corresponding to Mouse BRCA2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse, Rat |
1: 1500-1: 3000 |
brain |
|
IF |
Mouse, Rat |
1: 1500-1: 3000 |
brain |
Background
BRCA2, also named as FACD and FANCD1, is involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures.Defects in BRCA2 are a cause of genetic susceptibility to breast cancer (BC) which also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2).
Images
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Immunohistochemistry analysis of paraffin-embedded mouse brain using BRCA2 (GB111138) at dilution of 1: 2200 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using BRCA2 (GB111138) at dilution of 1: 2200 |
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Immunofluorescent analysis of paraffin-embedded mouse brain using BRCA2 (GB111138) at dilution of 1: 2200 |
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Immunofluorescent analysis of paraffin-embedded rat brain using BRCA2 (GB111138) at dilution of 1: 2200 |
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Immunofluorescent analysis of paraffin-embedded mouse brain using BRCA2 (GB111138) at dilution of 1: 2200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室