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Anti -IL-9 Rabbit pAb

价格: 在线咨询
货号:
DRF101664
产品规格:
100 μL
Applications:
Species:
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

IL-9 rabbit polyclonal

Protein full name

Interleukin-9

Synonyms

Il9, IL9, HP40, IL-9, P40, interleukin 9

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse IL-9

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P15247




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 1500-1: 3000

splenitis, enteritis

IF

Mouse, Rat

1: 750-1: 1500

splenitis, enteritis




Background


Il-9 is a cytokine secreted by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins namely STAT1, STAT3 and STAT5 and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. Interleukin-9 has also shown to inhibit melanoma growth in mice. Additionally, it gives rise to the multiplication of hematologic neoplasias and also Hodgkin's lymphoma in humans but IL-9 also has antitumor properties in solid tumors,for example melanoma.

         



Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse splenitis using

IL-9 (GB11684) at dilution of 1: 1500


image.png

Immunohistochemistry analysis of paraffin-embedded rat enteritis using

IL-9 (GB11684) at dilution of 1: 1500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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