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Anti -LAP2 Rabbit pAb

价格: 在线咨询
货号:
DRF101675
产品规格:
100 μL
Applications:
Species:
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

LAP2 rabbit polyclonal

Protein full name

Lamina-associated polypeptide 2, isoforms alpha/zeta

Synonyms

Thymopoietin isoforms alpha/zeta, TP alpha/zeta, Lap2, CMD1T, LAP2, LEMD4, PRO0868, Splenin Thymopentin, thymopoietin, TMPO, TP, TP alpha, TP5, TPRP isoform alpha

Immunogen

Recombinant protein corresponding to

Mouse LAP2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Predicted MW.

75 kDa

Observed MW.

51/75 kDa

Uniprot ID

P42166, Q61033




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, colon

IHC

Human, Mouse, Rat 1: 650-1: 1300

IF

Human, Mouse, Rat

1: 300-1: 1000

brain




Background


The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (α, β,γ, ε and δ) of mammalian LAP2 and three isoforms in Xenopus LAP2.




Images


图片 1.png

Western blot analysis of LAP2 (GB111948)

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: K562 cell lysate

Lane 4: Jurkat cell lysate

Lane 5: 293T cell lysate

Lane 6: Mouse liver tissue lysate

Lane 7: Mouse colon tissue lysate

Lane 8: Rat liver tissue lysate


Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using

LAP2 (GB111948) at dilution of 1: 600

Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using

LAP2 (GB111948) at dilution of 1: 600




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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