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产品详情
操作说明
注意事项
Product Information
| Description |
IL-22 rabbit polyclonal |
| Protein full name |
Interleukin-22 |
|
Synonyms |
IL22, IL-21, IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, interleukin 22 |
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse IL-22 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location |
Secreted |
| Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Mouse, Rat |
1:400-1:800 |
inflammatory lung |
|
IF |
Human, Mouse, Rat |
1:400-1:800 |
inflammatory lung |
Background
IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2receptor chains and further regulated by interactions with a soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (sIL-22R1). IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses.IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.
Images
|
Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using IL-22 (GB11259) at dilution of 1:400 |
|
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Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using IL-22 (GB11259) at dilution of 1:800
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室