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Anti -CD11c Rabbit pAb

价格: 在线咨询
货号:
DRF101804
产品规格:
100 μL
Applications:
Species:
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

CD11c rabbit polyclonal

Protein full name

Integrin alpha-X

Synonyms

ITGAX, CD11C, SLEB6, integrin subunit alpha X

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD11c 

Isotype

IgG

Predicted MW.

129 KDa

Observed MW.

150 KDa

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

P20702Q9QXH4



Applications


applications

species

dilution

Positive tissue

WB

Mouse

1: 500-1: 1000

thymus, spleen, inflammatory lung

IHC

Human, Mouse, Rat

1: 200-1: 400

tonsil, inflammatory lung, lung, splenitis

IF

Human, Mouse, Rat

1: 200-1: 400

pneumonia, spleen



Background


This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.




Images




Western blot analysis of CD11c(GB11059) at dilution of 1:1000

Lane 1: Raw264.7 cell lysate

Lane 2: Mouse spleen tissue lysate

Lane 3: Mouse inflammatory lung tissue lysate

Lane 4: Mouse thymus tissue lysate

Immunohistochemistry analysis of paraffin-embedded human tonsil using 

CD11c(GB11059) at dilution of 1: 400

Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using CD11c(GB11059) at dilution of 1: 400


Immunohistochemistry analysis of paraffin-embedded mouse lung using 

CD11c(GB11059) at dilution of 1: 400

Immunohistochemistry analysis of paraffin-embedded mouse splenitis using CD11c(GB11059) at dilution of 1: 400

Immunofluorescent analysis of paraformaldehyde-fixed rat inflammatory lung using CD11c(GB11059) at dilution of 1: 400

Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using 

CD11c(GB11059) at dilution of 1: 400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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