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Anti -CD45 Rabbit pAb

价格: 在线咨询
货号:
DRF101810
产品规格:
100 μL
Applications:
Species:
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

CD45 rabbit polyclonal

Protein full name

Receptor-type tyrosine-protein phosphatase C

Synonyms

PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD45 

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane,Membrane raft

Uniprot ID

P06800,P04157



Applications



applications

species

dilution

Positive tissue

IHC

Mouse, Rat

1: 1000-1: 3000

spleen,lung,liver

IF

Mouse, Rat

1: 2000-1: 4000

lymph node inflammation



Background



Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.




Images



Immunohistochemistry analysis of paraffin-embedded mouse liver using CD45(GB11066) at dilution of 1: 1500

Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD45(GB11066) at dilution of 1: 1500

Immunohistochemistry analysis of paraffin-embedded mouse lung using CD45(GB11066) at dilution of 1: 1500


Immunofluorescent analysis of paraformaldehyde-fixed mouse lymph node inflammation using CD31 (GB11063-2) at dilution of 1: 800




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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