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Anti -CD81 Rabbit pAb

价格: 在线咨询
货号:
DRF101816
产品规格:
100 μL
Applications:
Species:
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

CD81 rabbit polyclonal

Protein full name

CD81 antigen

Synonyms

26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, CD81, Tapa1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD81

Isotype

IgG

Purity

Affinity purification

Predicted MW.

26 kDa

Observed MW.

30 kDa

Uniprot ID

P60033, P35762, Q62745



Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

skeletal muscle



Background


CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells. In muscles, CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 appears to promote muscle cell fusion and support myotube maintenance. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. 




Images


图片 1.png

Western blot analysis of CD81 (GB111073) 

at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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