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产品详情
操作说明
注意事项
Product Information
|
Description |
CD22 rabbit polyclonal |
|
Protein full name |
B-cell receptor CD22 |
|
Synonyms |
CD22, SIGLEC-2, SIGLEC2, CD22 molecule |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human CD22 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
97 kDa |
|
Observed MW. |
125 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human |
1: 500-1: 1000 |
Jurkat, Hek293, MCF7 |
Background
CD22 is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the over-activation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Images
|
Western blot analysis of CD22 (GB11869) at dilution of 1: 1000 Lane 1: Jurkat cell lysate Lane 2: Hek293 cell lysate Lane 3: MCF7 cell lysate
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室