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Anti -CITED2 Rabbit pAb

价格: 在线咨询
货号:
KT012036
产品规格:
100 μL
Applications:
WB
Species:
MR
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

CITED2 rabbit polyclonal antibody

Protein full name

Cbp/p300-interacting transactivator 2

Synonyms

MSG-related protein 1, MRG-1, P35srj, Mrg1,  Cited2, Msg2

Immunogen

Recombinant protein corresponding to Mouse CITED2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

28 kDa

Observed MW.

28 kDa

Uniprot ID

O35740, Q99MA1




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, heart



Background


CITED2, also named as P35srj, is a cAMP-responsive element-binding protein (CBP)/p300-transactivator, with an ED(Glu/Asp)-rich C-terminal domain that acts as an important modulator in the development of the heart .It is proposed to be a negative regulator of HIF-1α through its competitive binding to the CH1 domain of CBP/p300, which mediated signaling and to a decrease in HIF-1-responsive genes such as VEGF. In addition, it is also a co-activator of the transcriptional activity of the TFAP2 isoform, which is an extensively expressed nuclear protein with functions in embryogenesis, inflammation, and stress responses.




Images


Picture 1.png

Western blot analysis of CITED2 (GB111129) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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