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Anti -HIF3 alpha/IPAS Rabbit pAb

价格: 在线咨询
货号:
KT012041
产品规格:
100 μL
Applications:
WB
Species:
H
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information

Description

HIF3 alpha rabbit polyclonal

Protein full name

Hypoxia-inducible factor 3-alpha

Synonyms

HIF3-alpha, bHLHe17, HIF3-alpha-1, PASD7, IPAS, Member of PAS protein 7, BHLHE17, HIF3A, MOP7

Immunogen

Recombinant protein corresponding to Human HIF3 alpha

Isotype

IgG

Purity

Affinity purification

Predicted MW.

72 kDa

Observed MW.

72 kDa

Uniprot ID

Q9Y2N7



Applications

Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

HUVEC, HeLa-hypoxia, HeLa



Background


Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.



Images

Western blot analysis of HIF3 alpha (GB111174) at dilution of 1: 1000
Lane 1: HUVEC cell lysate
Lane 2: Hela-hypoxia cell lysate
Lane 3: Hela cell lysate


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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